DISEASES

Disease-gene associations mined from literature

Literature associating PAEP and ovarian cyst

PAEP [ENSP00000417898]

Glycodelin; Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities . Glycodelin-C stimulates binding of spermatozoa to the zona pellucida . Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa . Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa . ECO:0000269|PubMed:17192260, ECO:0000269|PubMed:7531163,

Synonyms:  PAEP,  A0A024R8D8,  A6XNE0,  F2Z349,  H0Y4U4 ...

Linkouts:  STRING  Pharos  UniProt