DISEASES

Disease-gene associations mined from literature

Literature associating VAPB and frontotemporal dementia and/or amyotrophic lateral sclerosis-1

VAPB [ENSP00000417175]

Vesicle-associated membrane protein-associated protein B/C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.

Synonyms:  VAPB,  E5RK64,  O95292,  Q53XM7,  E5RK64p ...

Linkouts:  STRING  Pharos  UniProt  OMIM