DISEASES

Disease-gene associations mined from literature

Literature associating RIC1 and Hodgkin's lymphoma, nodular sclerosis

RIC1 [ENSP00000416696]

RAB6A-GEF complex partner protein 1; The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1.

Synonyms:  RIC1,  RIC1p,  hRIC1,  H0YFD4,  H0YFN7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM