DISEASES

Disease-gene associations mined from literature

Literature associating FSHB and aniridia

FSHB [ENSP00000416606]

Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways . Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432). ECO:0000269|PubMed:2494176, ECO:0000269|PubMed:407105,; Belongs to the glycoprotein hormones subunit beta family.

Synonyms:  FSHB,  A0A0F7RQE8,  P01225,  P01225p,  hP01225 ...

Linkouts:  STRING  Pharos  UniProt