DISEASES

Disease-gene associations mined from literature

Literature associating INTS12 and immature cataract

INTS12 [ENSP00000415433]

Integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex .

Synonyms:  INTS12,  INTS12p,  hINTS12,  A0A024RDK4,  A0A087WXN4 ...

Linkouts:  STRING  Pharos  UniProt