DISEASES

Disease-gene associations mined from literature

Literature associating ICAM2 and leukocyte adhesion deficiency 1

ICAM2 [ENSP00000415283]

Intercellular adhesion molecule 2; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

Synonyms:  ICAM2,  ICAM2p,  hICAM2,  J3KSR9,  J3QKR4 ...

Linkouts:  STRING  Pharos  UniProt