DISEASES

Disease-gene associations mined from literature

Literature associating MYO7B and microvillus inclusion disease

MYO7B [ENSP00000415090]

Unconventional myosin-VIIb; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli (Probable).

Synonyms:  MYO7B,  MYO7Bp,  hMYO7B,  B9A063,  C9JC21 ...

Linkouts:  STRING  Pharos  UniProt