Literature associating INPP5K and Parkinson's disease 20
INPP5K [ENSP00000413937]
Inositol polyphosphate 5-phosphatase K; Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate . Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate . Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle (By similarity). ECO:0000269|PubMed:16824732, ECO:0000269|PubMed:28190456,
Synonyms: INPP5K, INPP5Kp, hINPP5K, C9JQW8, C9JZB0 ...