DISEASES

Disease-gene associations mined from literature

Literature associating MICA and connective tissue disease

MICA [ENSP00000413079]

MHC class I polypeptide-related sequence A; Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. ECO:0000269|PubMed:11491531, ECO:0000269|PubMed:11777960,; Belongs to the MHC class I family. MIC subfamily.

Synonyms:  A0A024RCL3,  H0Y615,  Q96QC4,  H0Y615p,  hH0Y615 ...

Linkouts:  STRING  Pharos  UniProt