Literature associating MBD3 and progeria
MBD3 [ENSP00000412302]
Methyl-CpG-binding domain protein 3; Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself . Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides . Recruits histone deacetylases and DNA methyltransferases. ECO:0000269|PubMed:12124384, ECO:0000269|PubMed:18644863, ECO:0000269|PubMed:23361464, ECO:0000269|PubMed:24307175,
Synonyms: MBD3, MBD3p, hMBD3, A0A087WT34, A0A087WVG6 ...