DISEASES

Disease-gene associations mined from literature

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Literature associating LMOD2 and nemaline myopathy 10

LMOD2 [ENSP00000411932]

Leiomodin-2; Mediates nucleation of actin filaments and thereby promotes actin polymerization (PubMed:18403713, PubMed:26370058, PubMed:25250574, PubMed:26417072). Plays a role in the regulation of actin filament length (By similarity). Required for normal sarcomere organization in the heart, and for normal heart function . ECO:0000269|PubMed:18403713, ECO:0000269|PubMed:25250574,

Synonyms:  LMOD2,  LMOD2p,  hLMOD2,  C9J8F4,  Q6P5Q4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.