DISEASES

Disease-gene associations mined from literature

Literature associating CLDN4 and inflammatory bowel disease 20

CLDN4 [ENSP00000409544]

Claudin-4; Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.

Synonyms:  CLDN4,  CLDN4p,  hCLDN4,  O14493,  Q75L80 ...

Linkouts:  STRING  Pharos  UniProt