DISEASES

Disease-gene associations mined from literature

Literature associating DCD and Netherton syndrome

DCD [ENSP00000406773]

Survival-promoting peptide; DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C- terminal side of Arg and, to a lesser extent, Lys residues .

Synonyms:  DCD,  P81605,  P81605p,  hP81605,  117159 ...

Linkouts:  STRING  Pharos  UniProt