DISEASES

Disease-gene associations mined from literature

Literature associating RXFP1 and acrocallosal syndrome

RXFP1 [ENSP00000405841]

Relaxin receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP; Belongs to the G-protein coupled receptor 1 family.

Synonyms:  RXFP1,  RXFP1p,  hRXFP1,  A0A087WWV0,  A0A0A0MT52 ...

Linkouts:  STRING  Pharos  UniProt