Literature associating BMPR1B and testicular granulosa cell tumor
BMPR1B [ENSP00000401907]
Bone morphogenetic protein receptor type-1B; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Synonyms: BMPR1B, BMPR1Bp, hBMPR1B, D6RGW8, O00238 ...