DISEASES

Disease-gene associations mined from literature

Literature associating GAS2 and Griscelli syndrome type 2

GAS2 [ENSP00000401145]

Growth arrest-specific protein 2; May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).

Synonyms:  GAS2,  GAS2p,  hGAS2,  E9PM28,  E9PQ37 ...

Linkouts:  STRING  Pharos  UniProt