DISEASES

Disease-gene associations mined from literature

Literature associating CAPZB and epithelioid sarcoma

CAPZB [ENSP00000401010]

F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Synonyms:  CAPZB,  A0A384MR50,  B1AK85,  B1AK87,  B1AK88 ...

Linkouts:  STRING  Pharos  UniProt