DISEASES

Disease-gene associations mined from literature

Literature associating PRG4 and cartilage disease

PRG4 [ENSP00000399679]

Proteoglycan 4 C-terminal part; Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.

Synonyms:  PRG4,  PRG4p,  hPRG4,  A0A0U1RR20,  E9PLR3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM