DISEASES

Disease-gene associations mined from literature

Literature associating DDOST and autosomal recessive chronic granulomatous disease cytochrome b-positive type I

DDOST [ENSP00000399457]

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation. ; Belongs to the DDOST 48 kDa subunit family.

Synonyms:  DDOST,  A0A0C4DGS1,  P39656,  U3KQ84,  P39656p ...

Linkouts:  STRING  Pharos  UniProt