DISEASES

Disease-gene associations mined from literature

Literature associating ALKBH2 and salivary gland carcinoma

ALKBH2 [ENSP00000398181]

DNA oxidative demethylase ALKBH2; Dioxygenase that repairs alkylated DNA and RNA containing 1- methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single- stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:18432238,

Synonyms:  ALKBH2,  ALKBH2p,  hALKBH2,  F5GZZ0,  F5H5X2 ...

Linkouts:  STRING  Pharos  UniProt