DISEASES

Disease-gene associations mined from literature

Literature associating SFTPA1 and lung disease

SFTPA1 [ENSP00000397082]

Pulmonary surfactant-associated protein A1; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (By similarity).

Synonyms:  SFTPA1,  SFTPA1p,  hSFTPA1,  A0A024QZP2,  A0A0C4DG36 ...

Linkouts:  STRING  Pharos  UniProt  OMIM