DISEASES

Disease-gene associations mined from literature

Literature associating CLEC2A and clear cell basal cell carcinoma

CLEC2A [ENSP00000396163]

C-type lectin domain family 2 member A; Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti-apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.

Synonyms:  CLEC2A,  CLEC2Ap,  hCLEC2A,  Q6UVW9,  Q6UVW9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM