DISEASES

Disease-gene associations mined from literature

Literature associating NANOS1 and multiple synostoses syndrome

NANOS1 [ENSP00000393275]

Nanos homolog 1; May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. ; Belongs to the nanos family.

Synonyms:  NANOS1,  NANOS1p,  hNANOS1,  Q5T9H5,  Q8WY41 ...

Linkouts:  STRING  Pharos  UniProt  OMIM