DISEASES

Disease-gene associations mined from literature

Literature associating PTPN6 and leishmaniasis

PTPN6 [ENSP00000391592]

Tyrosine-protein phosphatase non-receptor type 6; Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

Synonyms:  PTPN6,  PTPN6p,  hPTPN6,  F5GXD4,  F5GY79 ...

Linkouts:  STRING  Pharos  UniProt  OMIM