Literature associating UNC80 and early infantile epileptic encephalopathy
UNC80 [ENSP00000391088]
Protein unc-80 homolog; Component of the NALCN sodium channel complex, required for channel regulation. This complex is a cation channel activated by neuropeptides substance P, neurotensin, and extracellular calcium that regulates neuronal excitability by controlling the sizes of NALCN- dependent sodium-leak current. UNC80 is essential for NALCN sensitivity to extracellular calcium.
Synonyms: UNC80, UNC80p, hUNC80, H3BLU5, Q8N2C7 ...