DISEASES

Disease-gene associations mined from literature

Literature associating SCN10A and fibromyalgia

SCN10A [ENSP00000390600]

Sodium channel, voltage-gated, type X, alpha subunit; Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium- selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms; Sodium voltage-gated channel alpha subunits

Synonyms:  SCN10A,  SCN10Ap,  hSCN10A,  Q9Y5Y9,  hPN3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM