Literature associating AGBL3 and scleroderma
AGBL3 [ENSP00000388275]
Cytosolic carboxypeptidase 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene- encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
Synonyms: AGBL3, AGBL3p, hAGBL3, F8W6Y5, F8W7R4 ...