DISEASES

Disease-gene associations mined from literature

Literature associating ZC3H12D and lymphoma

ZC3H12D [ENSP00000386616]

Probable ribonuclease ZC3H12D; May regulate cell growth likely by suppressing RB1 phosphorylation . May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages . Serve as a tumor suppressor in certain leukemia cells . Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation .

Synonyms:  ZC3H12D,  ZC3H12Dp,  hZC3H12D,  A2A288,  B7ZBA4 ...

Linkouts:  STRING  Pharos  UniProt