DISEASES

Disease-gene associations mined from literature

Literature associating SETD5 and autosomal dominant intellectual developmental disorder 23

SETD5 [ENSP00000385852]

Histone-lysine N-methyltransferase SETD5; Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 in vitro. The physiological significance of this activity is unclear. Probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. Acts as a regulator of histone acetylation during gene transcription.

Synonyms:  SETD5,  SETD5p,  hSETD5,  E7EWN3,  F2Z2J0 ...

Linkouts:  STRING  Pharos  UniProt