DISEASES

Disease-gene associations mined from literature

Literature associating UBAC2 and iridocyclitis

UBAC2 [ENSP00000383911]

Ubiquitin-associated domain-containing protein 2; Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets . In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin- mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 .

Synonyms:  UBAC2,  UBAC2p,  hUBAC2,  A0A024RE02,  A0A087WXT1 ...

Linkouts:  STRING  Pharos  UniProt