DISEASES

Disease-gene associations mined from literature

Literature associating ADA2 and lymphoproliferative syndrome

ADA2 [ENSP00000382731]

Adenosine deaminase 2; Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity.

Synonyms:  ADA2,  ADA2p,  hADA2,  A0A087X0I3,  A0A3B3IRN1 ...

Linkouts:  STRING  Pharos  UniProt