Literature associating ASCC2 and large intestine adenocarcinoma
ASCC2 [ENSP00000380877]
Activating signal cointegrator 1 complex subunit 2; Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains . Part of the ASC-1 complex that enhances NF- kappa-B, SRF and AP1 transactivation .
Synonyms: ASCC2, ASCC2p, hASCC2, A0A024R1F9, B1AH59 ...