DISEASES

Disease-gene associations mined from literature

Literature associating CCNF and amyotrophic lateral sclerosis

CCNF [ENSP00000380256]

Cyclin-F; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. ; Belongs to the cyclin family. Cyclin AB subfamily.

Synonyms:  CCNF,  H0Y2P7,  H3BUD3,  P41002,  H0Y2P7p ...

Linkouts:  STRING  Pharos  UniProt  OMIM