DISEASES

Disease-gene associations mined from literature

Literature associating ATF7IP2 and expressive language disorder

ATF7IP2 [ENSP00000379808]

Activating transcription factor 7-interacting protein 2; Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable); Belongs to the MCAF family.

Synonyms:  ATF7IP2,  ATF7IP2p,  hATF7IP2,  B4DKH3,  F5GY73 ...

Linkouts:  STRING  Pharos  UniProt