Literature associating RAB27A and X-linked lymphoproliferative syndrome 1
RAB27A [ENSP00000379601]
Ras-related protein Rab-27A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion . Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Synonyms: RAB27A, RAB27Ap, hRAB27A, A2RU94, H3BN55 ...