Literature associating YWHAZ and idiopathic generalized epilepsy 11
YWHAZ [ENSP00000379287]
14-3-3 protein zeta/delta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation . In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity). ECO:0000269|PubMed:15071501, ECO:0000269|PubMed:15644438, ECO:0000269|PubMed:16376338, ECO:0000269|PubMed:16959763,; Belongs to the 14-3-3 family.
Synonyms: YWHAZ, B0AZS6, B7Z2E6, D0PNI1, E5RGE1 ...