Literature associating COA1 and cytochrome-c oxidase deficiency disease
COA1 [ENSP00000379218]
Cytochrome c oxidase assembly factor 1 homolog; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV.
Synonyms: COA1, COA1p, hCOA1, A0A024RA60, C9J6J1 ...