DISEASES

Disease-gene associations mined from literature

Literature associating TRPS1 and hypertension and brachydactyly syndrome

TRPS1 [ENSP00000379065]

Zinc finger transcription factor Trps1; Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.

Synonyms:  TRPS1,  TRPS1p,  hTRPS1,  A0A1D5RMP4,  C9J6L7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM