DISEASES

Disease-gene associations mined from literature

Literature associating SULT1A1 and autosomal dominant intellectual developmental disorder 2

SULT1A1 [ENSP00000378972]

Sulfotransferase 1A1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.

Synonyms:  SULT1A1,  SULT1A1p,  hSULT1A1,  H3BMH9,  H3BQX5 ...

Linkouts:  STRING  Pharos  UniProt