DISEASES

Disease-gene associations mined from literature

Literature associating CXXC4 and Miles-Carpenter syndrome

CXXC4 [ENSP00000378248]

CXXC-type zinc finger protein 4; Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1 (By similarity). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl- CpG .

Synonyms:  CXXC4,  CXXC4p,  hCXXC4,  J9JIF5,  J9JIF5p ...

Linkouts:  STRING  Pharos  UniProt