DISEASES

Disease-gene associations mined from literature

Literature associating CBX1 and primary hyperoxaluria type 1

CBX1 [ENSP00000377060]

Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.

Synonyms:  CBX1,  CBX1p,  hCBX1,  B5MD17,  C9JWS9 ...

Linkouts:  STRING  Pharos  UniProt