Literature associating TTLL6 and Joubert syndrome
TTLL6 [ENSP00000377043]
Tubulin polyglutamylase TTLL6; Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Generates long side-chains. Generates polyglutamylation of CGAS, leading to impair the DNA-binding activity of CGAS.
Synonyms: TTLL6, TTLL6p, hTTLL6, F6QD81, F8W896 ...