DISEASES

Disease-gene associations mined from literature

Literature associating BCL2L11 and spastic hemiplegia

BCL2L11 [ENSP00000376943]

Bcl-2-like protein 11; Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase- mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis; Belongs to the Bcl-2 family.

Synonyms:  BCL2L11,  BCL2L11p,  hBCL2L11,  A0A0A0MRE7,  A0A0C4DH20 ...

Linkouts:  STRING  Pharos  UniProt  OMIM