DISEASES

Disease-gene associations mined from literature

Literature associating SCN3B and sinoatrial node disease

SCN3B [ENSP00000376523]

Sodium channel subunit beta-3; Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity).

Synonyms:  SCN3B,  SCN3Bp,  hSCN3B,  A0A024R3H7,  Q9NY72 ...

Linkouts:  STRING  Pharos  UniProt