DISEASES

Disease-gene associations mined from literature

Literature associating PDCD10 and hemangioma of liver

PDCD10 [ENSP00000376506]

Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity . Important for cell migration, and for normal structure and assembly of the Golgi complex . Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). ECO:0000269|PubMed:15543491, ECO:0000269|PubMed:17360971,; Belongs to the PDCD10 family.

Synonyms:  PDCD10,  PDCD10p,  hPDCD10,  C9J363,  C9J5C3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM