DISEASES

Disease-gene associations mined from literature

Literature associating DYNLL1 and retinitis pigmentosa 3

DYNLL1 [ENSP00000376297]

Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1; Belongs to the dynein light chain family.

Synonyms:  DYNLL1,  DYNLL1p,  hDYNLL1,  DNCL1,  F8VRV5 ...

Linkouts:  STRING  Pharos  UniProt