DISEASES

Disease-gene associations mined from literature

Literature associating DNM2 and autosomal dominant centronuclear myopathy

DNM2 [ENSP00000373905]

Dynamin-2; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis . Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity).

Synonyms:  DNM2,  DNM2p,  hDNM2,  K7EMQ3,  K7EMR9 ...

Linkouts:  STRING  Pharos  UniProt