DISEASES

Disease-gene associations mined from literature

Literature associating FBXO25 and palmoplantar keratoderma-esophageal carcinoma syndrome

FBXO25 [ENSP00000372274]

F-box only protein 25; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity).

Synonyms:  FBXO25,  FBXO25p,  hFBXO25,  A0A024QZ88,  E5RFH9 ...

Linkouts:  STRING  Pharos  UniProt