DISEASES

Disease-gene associations mined from literature

Literature associating NOP2 and restrictive cardiomyopathy

NOP2 [ENSP00000371858]

Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; Involved in ribosomal large subunit assembly . S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

Synonyms:  NOP2,  NOP2p,  hNOP2,  F5GWB7,  F5GYR3 ...

Linkouts:  STRING  Pharos  UniProt