DISEASES

Disease-gene associations mined from literature

Literature associating NIN and Meckel syndrome

NIN [ENSP00000371472]

Ninein; Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells (PubMed:15190203, PubMed:23386061). May also act as a centrosome maturation factor . May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome . Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules . Required for centriole organization and microtubule anchoring at the mother centriole .

Synonyms:  NIN,  A0A0B4J215,  C9J066,  E9PJH9,  E9PN67 ...

Linkouts:  STRING  Pharos  UniProt  OMIM